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Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues

Neutrophil elastase is secreted by inflammatory cells during airway inflammation and can elicit airway hyperreactivity in vivo. Elastase can degrade multiple components of the extracellular matrix. We hypothesized that elastase might disrupt the connections between airway smooth muscle (ASM) cells a...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Lockett, Angelia D., Wu, Yidi, Gunst, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966780/
https://ncbi.nlm.nih.gov/pubmed/29212803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00334.2017
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