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Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice

Hyperandrogenemia and hyperinsulinemia are believed to play prominent roles in polycystic ovarian syndrome (PCOS). We explored the effects of low-dose dihydrotestosterone (DHT), a model of PCOS, on insulin signaling in metabolic and reproductive tissues in a female mouse model. Insulin resistance in...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Andrisse, Stanley, Billings, Katelyn, Xue, Ping, Wu, Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966754/
https://ncbi.nlm.nih.gov/pubmed/29351485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00195.2017
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