Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

Kinetochores are multi-protein complexes that power chromosome movements by tracking microtubules plus-ends in the mitotic spindle. Human kinetochores bind up to 20 microtubules, even though single microtubules can generate sufficient force to move chromosomes. Here, we show that high microtubule oc...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Dudka, Damian, Noatynska, Anna, Smith, Chris A., Liaudet, Nicolas, McAinsh, Andrew D., Meraldi, Patrick
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966435/
https://ncbi.nlm.nih.gov/pubmed/29795284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04427-x
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