Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity

The development of nephrotoxicity largely limits the clinical use of chemotherapy. MiRNAs are able to target various genes and involved in the regulation of diverse cellular processes, including cell apoptosis and death. Our study showed that miR-181a expression was significantly increased after 5-f...

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Опубликовано в: :Cell Death Dis
Главные авторы: Liu, Xiao-Yun, Zhang, Fei-Ran, Shang, Jin-Yan, Liu, Ying-Ying, Lv, Xiao-Fei, Yuan, Jia-Ni, Zhang, Ting-Ting, Li, Kai, Lin, Xiao-Chun, Liu, Xiu, Lei, Qingqing, Fu, Xiao-Dong, Zhou, Jia-Guo, Liang, Si-Jia
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966400/
https://ncbi.nlm.nih.gov/pubmed/29795190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0677-8
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