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Identification of natural compounds targeting Annexin A2 with an anti-cancer effect

Annexin A2, a multifunctional tumor associated protein, promotes nuclear factor-kappa B (NF-κB) activation by interacting with NF-κB p50 subunit and facilitating its nuclear translocation. Here we demonstrated that two ginsenosides Rg5 (G-Rg5) and Rk1 (G-Rk1), with similar structure, directly bound...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Wang, Yu-Shi, Li, He, Li, Yang, Zhu, Hongyan, Jin, Ying-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966357/
https://ncbi.nlm.nih.gov/pubmed/29508276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0513-z
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