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Targeting the lysosome for cancer therapy

Lysosomes are the recycling centers of the cell where organelles and proteins are degraded during autophagy and macropinocytosis; they also serve as signaling hubs that control the activity of the mechanistic target of rapamycin complex I (mTORC1). In this issue, Rebecca and colleagues report the de...

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Bibliografische gegevens
Gepubliceerd in:Cancer Discov
Hoofdauteurs: Towers, Christina G., Thorburn, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966281/
https://ncbi.nlm.nih.gov/pubmed/29097619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0996
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