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Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists

The mechanism of prostate cancer (PCa) progression towards the hormone refractory state remains poorly understood. Treatment options for such patients are limited and present a major clinical challenge. Previously, δ-catenin was reported to promote PCa cell growth in vitro and its increased level is...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Piyan, Schaefer-Klein, Janet, Cheville, John C., Vasmatzis, George, Kovtun, Irina V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966253/
https://ncbi.nlm.nih.gov/pubmed/29849951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25319
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