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Death and population dynamics affect mutation rate estimates and evolvability under stress in bacteria

The stress-induced mutagenesis hypothesis postulates that in response to stress, bacteria increase their genome-wide mutation rate, in turn increasing the chances that a descendant is able to better withstand the stress. This has implications for antibiotic treatment: exposure to subinhibitory doses...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Frenoy, Antoine, Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966242/
https://ncbi.nlm.nih.gov/pubmed/29750784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005056
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