Abnormal expression of p27kip1 protein in levator ani muscle of aging women with pelvic floor disorders – a relationship to the cellular differentiation and degeneration

BACKGROUND: Pelvic floor disorders affect almost 50% of aging women. An important role in the pelvic floor support belongs to the levator ani muscle. The p27/kip1 (p27) protein, multifunctional cyclin-dependent kinase inhibitor, shows changing expression in differentiating skeletal muscle cells duri...

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Autori principali: Bukovsky, Antonin, Copas, Pleas, Caudle, Michael R, Cekanova, Maria, Dassanayake, Tamara, Asbury, Bridgett, Van Meter, Stuart E, Elder, Robert F, Brown, Jeffrey B, Cross, Stephanie B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2001
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC59662/
https://ncbi.nlm.nih.gov/pubmed/11696252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6890-1-4
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