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Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL

The ability to respond to changes in pH is critical for all organisms. In Salmonella enterica, the sensor PhoQ responds to a mildly acidic pH by phosphorylating, and thereby activating, the virulence regulator PhoP. This PhoP/PhoQ two-component system is conserved in a subset of Gram-negative bacter...

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Bibliografski detalji
Izdano u:Sci Signal
Glavni autori: Choi, Jeongjoon, Groisman, Eduardo A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966036/
https://ncbi.nlm.nih.gov/pubmed/28851823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan6284
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