Genetic variation in P2RX7 and pain tolerance

P2X7 is a nonselective cation channel activated by extracellular ATP. P2X7 activation contributes to the proinflammatory response to injury or bacterial invasion and mediates apoptosis. Recently, P2X7 function has been linked to chronic inflammatory and neuropathic pain. P2X7 may contribute to pain...

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Dettagli Bibliografici
Pubblicato in:Pain
Autori principali: Kambur, Oleg, Kaunisto, Mari A., Winsvold, Bendik S., Wilsgaard, Tom, Stubhaug, Audun, Zwart, John A., Kalso, Eija, Nielsen, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965926/
https://ncbi.nlm.nih.gov/pubmed/29470314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001188
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