Metabolic benefits of inhibition of p38α in white adipose tissue in obesity

p38 has long been known as a central mediator of protein kinase A (PKA) signaling in brown adipocytes, which positively regulate the transcription of uncoupling protein 1 (UCP-1). However, the physiological role of p38 in adipose tissues, especially the white adipose tissue (WAT), is largely unknown...

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Vydáno v:PLoS Biol
Hlavní autoři: Zhang, Shengjie, Cao, Hongchao, Li, Yan, Jing, Yanyan, Liu, Shengnan, Ye, Cheng, Wang, Hui, Yu, Shuxian, Peng, Chengyuan, Hui, Lijian, Wang, Yu-cheng, Zhang, Haibing, Guo, Feifan, Zhai, Qiwei, Huang, Ruimin, Zhang, Ling, Jiang, Jingjing, Liu, Wei, Ying, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965899/
https://ncbi.nlm.nih.gov/pubmed/29750781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2004225
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