Methodology and effects of repeated intranasal delivery of DNSP-11 in awake Rhesus macaques

BACKGROUND: To determine if the intranasal delivery of neuroactive compounds is a viable, long-term treatment strategy for progressive, chronic neurodegenerative disorders, such as Parkinson’s disease (PD), intranasal methodologies in preclinical models comparable to humans are needed. NEW METHOD: W...

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Pubblicato in:J Neurosci Methods
Autori principali: Stenslik, M.J., Evans, A., Pomerleau, F., Weeks, R., Huettl, P., Foreman, E., Turchan-Cholewo, J., Andersen, A., Cass, W.A., Zhang, Z., Grondin, R.C., Gash, D.M., Gerhardt, G.A., Bradley, L.H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965701/
https://ncbi.nlm.nih.gov/pubmed/29614295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2018.03.006
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