Inhibition of KSHV infected primary effusion lymphomas in NOD/SCID mice by γ-secretase inhibitor

Primary effusion lymphoma (PEL) is a common cancer in AIDS patients closely associated with Kaposi’s sarcoma-associated herpesvirus (KSHV). Previously, we showed that KSHV latency associated nuclear antigen (LANA) stabilizes intracellular activated Notch1 (ICN) involved in maintenance of the maligna...

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Publicat a:Cancer Biol Ther
Autors principals: Lan, Ke, Murakami, Masanao, Bajaj, Bharat, Kaul, Rajeev, He, Zhiheng, Gan, Runliang, Feldman, Michael, Robertson, Erle S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965683/
https://ncbi.nlm.nih.gov/pubmed/19783901
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