Calcium Channel Blockers as Drug Repurposing Candidates for Gestational Diabetes: Mining large scale genomic and electronic health records data to repurpose medications

New therapeutic approaches are needed for gestational diabetes mellitus (GDM), but must show safety and efficacy in a historically understudied population. We studied associations between electronic medical record (EMR) phenotypes and genetic variants to uncover drugs currently considered safe in pr...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Goldstein, Jeffery A., Bastarache, Lisa A., Denny, Joshua C., Roden, Dan M., Pulley, Jill M., Aronoff, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965292/
https://ncbi.nlm.nih.gov/pubmed/29448118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.02.013
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