The Plasminogen Receptor, Plg-R(KT,) is Essential for Mammary Lobuloalveolar Development and Lactation

BACKGROUND: Lactational competence requires plasminogen, the zymogen of the serine protease, plasmin. Plg-R(KT) is a unique transmembrane plasminogen receptor that promotes plasminogen activation to plasmin on cell surfaces. Plg-R(KT)(−/−) mice are viable, but no offspring of Plg-R(KT)(−/−) female m...

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Pubblicato in:J Thromb Haemost
Autori principali: Miles, Lindsey A., Baik, Nagyung, Bai, Hongdong, Makarenkova, Helen P., Kiosses, William B., Krajewski, Stan, Castellino, Francis J., Valenzuela, Alex, Varki, Nissi M., Mueller, Barbara M., Parmer, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965281/
https://ncbi.nlm.nih.gov/pubmed/29495105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13988
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