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All in the family: repeats and ALS/FTD

In 2011, an intronic (G4C2)•(G2C4) expansion was shown to cause the most common form of amyotrophic lateral sclerosis and frontotemporal dementia. This discovery linked ALS with a clinically distinct form of dementia and a larger group of microsatellite repeat diseases, and catalyzed basic and trans...

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Pubblicato in:Trends Neurosci
Autori principali: Pattamatta, Amrutha, Cleary, John D., Ranum, Laura P.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965280/
https://ncbi.nlm.nih.gov/pubmed/29703376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2018.03.010
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