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Model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients

The noninferiority of direct oral factor Xa (FXa) inhibitors (rivaroxaban, apixaban, and edoxaban) in treatment of atrial fibrillation were demonstrated compared with warfarin by several large clinical trials; however, subsequent meta-analyses reported a higher risk of major bleeding with rivaroxaba...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Yoshioka, Hideki, Sato, Hiromi, Hatakeyama, Hiroto, Hisaka, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965044/
https://ncbi.nlm.nih.gov/pubmed/29760204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017013805
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