Establishment of lung cancer patient-derived xenograft models and primary cell lines for lung cancer study

BACKGROUND: The overall 5-year survival rate of lung cancer is about 15% even with therapeutic drugs like tyrosine kinase inhibitors. Ideal models are urgently needed for exploring mechanisms and finding new drugs. Patient-derived xenografts (PDX) models and primary cells are both used to screen the...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Jiang, Yanan, Zhao, Jimin, Zhang, Yi, Li, Ke, Li, Tiepeng, Chen, Xinhuan, Zhao, Simin, Zhao, Song, Liu, Kangdong, Dong, Ziming
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964929/
https://ncbi.nlm.nih.gov/pubmed/29788985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1516-5
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