Alterations in NO- and PGI(2)- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation

BACKGROUND: Patients with cancer develop endothelial dysfunction and subsequently display a higher risk of cardiovascular events. The aim of the present work was to examine changes in nitric oxide (NO)- and prostacyclin (PGI(2))-dependent endothelial function in the systemic conduit artery (aorta),...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Buczek, E., Denslow, A., Mateuszuk, L., Proniewski, B., Wojcik, T., Sitek, B., Fedorowicz, A., Jasztal, A., Kus, E., Chmura- Skirlinska, A., Gurbiel, R., Wietrzyk, J., Chlopicki, S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964697/
https://ncbi.nlm.nih.gov/pubmed/29788918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4445-z
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