Sister Chromatid Exchange and Genomic Instability in Soft Tissue Sarcomas: Potential Implications for Response to DNA-Damaging Treatments

Sarcomas are rare heterogeneous malignancies of mesenchymal origin characterised by complex karyotypes but no specific abnormalities. Recurrence is common, and metastatic disease carries poor survival despite standard DNA-damaging radiotherapy or chemotherapy. DNA double-strand breaks (DSBs) are eit...

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Detalhes bibliográficos
Publicado no:Sarcoma
Main Authors: Salawu, Abdulazeez, Wright, Kristin, Al-Kathiri, Afnan, Wyld, Lynda, Reed, Malcolm, Sisley, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964616/
https://ncbi.nlm.nih.gov/pubmed/29853780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3082526
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