Mesenchymal Stem Cells Promote the Osteogenesis in Collagen-Induced Arthritic Mice through the Inhibition of TNF-α

OBJECTIVE: To investigate the effects of umbilical cord mesenchymal stem cell (UC-MSC) transplantation on joint damage and osteoporosis in collagen-induced arthritis (CIA) mice and to explore the mechanisms by which UC-MSCs modulate the osteogenic differentiation. METHODS: CIA mice were divided into...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Liu, Chang, Zhang, Huayong, Tang, Xiaojun, Feng, Ruihai, Yao, Genhong, Chen, Weiwei, Li, Wenchao, Liang, Jun, Feng, Xuebing, Sun, Lingyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964571/
https://ncbi.nlm.nih.gov/pubmed/29853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4069032
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