Myeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis

Rodents are a natural host for the dimorphic pathogenic fungi Coccidioides immitis and Coccidioides posadasii, and mice are a good model for human infection. Humans and rodents both express Dectin-1 and Toll-like receptor 2 (TLR2) on myeloid cells, and those receptors collaborate to maximize the cyt...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Viriyakosol, Suganya, Walls, Lorraine, Okamoto, Sharon, Raz, Eyal, Williams, David L., Fierer, Joshua
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964525/
https://ncbi.nlm.nih.gov/pubmed/29610256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00028-18
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