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Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome

Synthetic biology tools, such as modular parts and combinatorial DNA assembly, are routinely used to optimise the productivity of heterologous metabolic pathways for biosynthesis or substrate utilisation, yet it is well established that host strain background is just as important for determining pro...

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發表在:Nat Commun
Main Authors: Blount, B. A., Gowers, G-O. F., Ho, J. C. H., Ledesma-Amaro, R., Jovicevic, D., McKiernan, R. M., Xie, Z. X., Li, B. Z., Yuan, Y. J., Ellis, T.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964169/
https://ncbi.nlm.nih.gov/pubmed/29789540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03143-w
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