Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of these infections is a major hurdle of therapy because pulmonary NTM infections can persist in biofilms or as intrace...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zhang, Jimin, Leifer, Franziska, Rose, Sasha, Chun, Dung Yu, Thaisz, Jill, Herr, Tracey, Nashed, Mary, Joseph, Jayanthi, Perkins, Walter R., DiPetrillo, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964161/
https://ncbi.nlm.nih.gov/pubmed/29867826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00915
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