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Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota

Systemic chronic hypoxia is a feature of many diseases and may influence the communication between bone marrow (BM) and gut microbiota. Here we analyse patients with cyanotic congenital heart disease (CCHD) who are experiencing chronic hypoxia and characterize the association between bone marrow mes...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Xing, Junyue, Ying, Yongquan, Mao, Chenxi, Liu, Yiwei, Wang, Tingting, Zhao, Qian, Zhang, Xiaoling, Yan, Fuxia, Zhang, Hao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964076/
https://ncbi.nlm.nih.gov/pubmed/29789585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04453-9
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