Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma

By restriction fragment length polymorphism analysis, we examined loss of heterozygosity at 34 loci on 23 chromosomes in 35 surgically resected human hepatocellular carcinomas. Allele losses at the HP locus on chromosome 16q22 and at the MT2P1 locus on chromosome 4p11‐q21 were detected in 57% (8/14)...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Zhang, Wandong, Hirohashi, Setsuo, Tsuda, Hitoshi, Shimosato, Yukio, Yokota, Jun, Terada, Masaaki, Sugimura, Takashi
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1990
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963891/
https://ncbi.nlm.nih.gov/pubmed/1970554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02534.x
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