Loss of PTEN promotes formation of signaling-capable clathrin-coated pits

Defective endocytosis and vesicular trafficking of signaling receptors has recently emerged as a multifaceted hallmark of malignant cells. Clathrin-coated pits (CCPs) display highly heterogeneous dynamics on the plasma membrane where they can take from 20 s to over 1 min to form cytosolic coated ves...

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Udgivet i:J Cell Sci
Main Authors: Rosselli-Murai, Luciana K., Yates, Joel A., Yoshida, Sei, Bourg, Julia, Ho, Kenneth K. Y., White, Megan, Prisby, Julia, Tan, Xinyu, Altemus, Megan, Bao, Liwei, Wu, Zhi-Fen, Veatch, Sarah L., Swanson, Joel A., Merajver, Sofia D., Liu, Allen P.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963840/
https://ncbi.nlm.nih.gov/pubmed/29588397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208926
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