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Molecular imaging of tumor photoimmunotherapy: Evidence of photosensitized tumor necrosis and hemodynamic changes

Near-infrared photoimmunotherapy (NIR PIT) employs the photoabsorbing dye IR700 conjugated to antibodies specific for cell surface epidermal growth factor receptor (EGFR). NIR PIT has shown highly selective cytotoxicity in vitro and in vivo. Cell necrosis is thought to be the main mode of cytotoxici...

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Dades bibliogràfiques
Publicat a:Free Radic Biol Med
Autors principals: Kishimoto, Shun, Oshima, Nobu, Yamamoto, Kazutoshi, Munasinghe, Jeeva, Ardenkjaer-Larsen, Jan Henrik, Mitchell, James B., Choyke, Peter L., Krishna, Murali C.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963721/
https://ncbi.nlm.nih.gov/pubmed/29289705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.12.034
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