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Dynamic opposition of clustered proteins stabilizes cortical polarity in the C. elegans zygote

Dynamic maintenance of cell polarity is essential for development and physiology. Here we combine experiments and modeling to elucidate mechanisms that maintain cortical polarity in the C. elegans zygote. We show that polarity is dynamically stabilized by two coupled cross-inhibitory feedback loops:...

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Publicat a:Dev Cell
Autors principals: Sailer, Anne, Anneken, Alexander, Li, Younan, Lee, Sam, Munro, Edwin
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963695/
https://ncbi.nlm.nih.gov/pubmed/26460948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.09.006
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