PRIMUS: improving pedigree reconstruction using mitochondrial and Y haplotypes

Summary: PRIMUS is a pedigree reconstruction algorithm that uses estimates of genome-wide identity by descent to reconstruct pedigrees consistent with observed genetic data. However, when genetic data for individuals within a pedigree are missing, often multiple pedigrees can be reconstructed that f...

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Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Staples, Jeffrey, Ekunwe, Lynette, Lange, Ethan, Wilson, James G., Nickerson, Deborah A., Below, Jennifer E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Applications Notes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963362/
https://ncbi.nlm.nih.gov/pubmed/26515822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv618
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