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Regulation of Large Number of Weak Targets—New Insights from Twin-microRNAs
Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the “small...
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| 發表在: | Genome Biol Evol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963297/ https://ncbi.nlm.nih.gov/pubmed/29688430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy079 |
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