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Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson’s disease

BACKGROUND: Administration of granulocyte-macrophage colony-stimulating factor (GM-CSF) increases regulatory T cell (Treg) number and function with control of neuroinflammation and neuronal protection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of Parkinson’s disease (PD). Recen...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Schutt, Charles R., Gendelman, Howard E., Mosley, R. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963189/
https://ncbi.nlm.nih.gov/pubmed/29783988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0255-7
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