Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes

[Image: see text] One of the areas in which bioorthogonal chemistry—chemistry performed inside a cell or organism—has become of pivotal importance is in the study of host–pathogen interactions. The incorporation of bioorthogonal groups into the cell wall or proteome of intracellular pathogens has al...

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Библиографические подробности
Опубликовано в: :ACS Chem Biol
Главные авторы: Bakkum, Thomas, van Leeuwen, Tyrza, Sarris, Alexi J. C., van Elsland, Daphne M., Poulcharidis, Dimitrios, Overkleeft, Herman S., van Kasteren, Sander I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2018
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962927/
https://ncbi.nlm.nih.gov/pubmed/29693370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00355
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