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MCC950, the Selective Inhibitor of Nucleotide Oligomerization Domain-Like Receptor Protein-3 Inflammasome, Protects Mice against Traumatic Brain Injury

Nucleotide oligomerization domain (NOD)-like receptor protein-3 (NLRP3) inflammasome may intimately contribute to sustaining damage after traumatic brain injury (TBI). This study aims to examine whether specific modulation of NLPR3 inflammasome by MCC950, a novel selective NLRP3 inhibitor, confers p...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Ismael, Saifudeen, Nasoohi, Sanaz, Ishrat, Tauheed
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962912/
https://ncbi.nlm.nih.gov/pubmed/29295651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2017.5344
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