Monoclonal antibody 3H11 chimeric antigen receptors enhance T cell effector function and exhibit efficacy against gastric cancer

Although chimeric antigen receptor T cell (CAR-T) therapies for certain types of solid tumors have been used in clinical trials, novel CARs that are able to target gastric cancer (GC) are still required. In our previous study, monoclonal antibody 3H11 (mAb 3H11), generated from immunization with fiv...

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I publikationen:Oncol Lett
Huvudupphovsmän: Han, Haibo, Wang, Shanshan, Hu, Ying, Li, Zhaowei, Yang, Wei, Lv, Yunwei, Wang, Limin, Zhang, Lianhai, Ji, Jiafu
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2018
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962852/
https://ncbi.nlm.nih.gov/pubmed/29849787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8255
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