Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma

Constant exposure to allergen triggers destructive type 2 cell-mediated inflammation. The effect of allergen specific immunotherapy (SIT) in maintaining airway epithelial barrier function in asthma remains unknown. In the current study, we showed that SIT maintained airway epithelial homeostasis in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yuan, Xiefang, Wang, Junyi, Li, Yin, He, Xiang, Niu, Bin, Wu, Dehong, lan, Nan, Wang, Xiaoyun, Zhang, Yun, Dai, Xi, Wang, Xing, Liu, Zhigang, Li, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962552/
https://ncbi.nlm.nih.gov/pubmed/29784924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26221-x
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