Bacillus Calmette–Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer

BACKGROUND: Programmed death-ligand 1 (PD-L1) is a critical immune checkpoint molecule which promotes immunosuppression by binding to PD-1 on T-cells in tumor immunity. We have previously identified that activation of toll like receptor 4 (TLR-4), which serves an important role in the induction of a...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Yonghua, Liu, Jing, Yang, Xuecheng, Liu, Yanan, Liu, Yong, Li, Yanjiang, Sun, Lijiang, Yang, Xiaokun, Niu, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962256/
https://ncbi.nlm.nih.gov/pubmed/29844686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S165840
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