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A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases

Upon infection, viral nucleic acids are recognized by germline-encoded pattern-recognition receptors (PRRs), and cytosolic retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) that initiate signaling pathways resulting in the production of type I IFN and pro-inflammatory cytokines. Binding o...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Gupta, Soham, Ylä-Anttila, Päivi, Masucci, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961920/
https://ncbi.nlm.nih.gov/pubmed/29799549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2018.05.633
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