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PolNet: A Tool to Quantify Network-Level Cell Polarity and Blood Flow in Vascular Remodeling

In this article, we present PolNet, an open-source software tool for the study of blood flow and cell-level biological activity during vessel morphogenesis. We provide an image acquisition, segmentation, and analysis protocol to quantify endothelial cell polarity in entire in vivo vascular networks....

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Bernabeu, Miguel O., Jones, Martin L., Nash, Rupert W., Pezzarossa, Anna, Coveney, Peter V., Gerhardt, Holger, Franco, Claudio A.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961748/
https://ncbi.nlm.nih.gov/pubmed/29742399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.032
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