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Tanshinol ameliorates CCl(4)-induced liver fibrosis in rats through the regulation of Nrf2/HO-1 and NF-κB/IκBα signaling pathway

Tanshinol, a water-soluble component isolated from Salvia miltiorrhiza Bunge, has a variety of biological activities involving anti-fibrotic effect. However, the exact role and the underlying mechanisms remain largely unclear. This study mainly focused on the anti-hepatic fibrotic activities and mec...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Wang, Rong, Wang, Jing, Song, Fuxing, Li, Shengnan, Yuan, Yongfang
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961642/
https://ncbi.nlm.nih.gov/pubmed/29844659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S159546
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