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Nuclear Transport and Accumulation of Smad Proteins Studied by Single-Molecule Microscopy
Nuclear translocation of stimulated Smad heterocomplexes is a critical step in the signal transduction of transforming growth factor β (TGF-β) from transmembrane receptors into the nucleus. Specifically, normal nuclear accumulation of Smad2/Smad4 heterocomplexes induced by TGF-β1 is involved in carc...
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| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961462/ https://ncbi.nlm.nih.gov/pubmed/29742417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.018 |
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