Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

PURPOSE: To identify genetic risk factors contributing to central corneal thickness (CCT) in individuals from South India, a population with a high prevalence of ocular disorders. METHODS: One hundred ninety-five individuals from 15 large South Indian pedigrees were genotyped using the Omni2.5 bead...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Fan, Bao Jian, Chen, Xueli, Sondhi, Nisha, Sharmila, P. Ferdinamarie, Soumittra, Nagasamy, Sripriya, Sarangapani, Sacikala, Srinivasan, Asokan, Rashima, Friedman, David S., Pasquale, Louis R., Gao, X. Raymond, Vijaya, Lingam, Cooke Bailey, Jessica, Vitart, Veronique, MacGregor, Stuart, Hammond, Christopher J., Khor, Chiea Chuen, Haines, Jonathan L., George, Ronnie, Wiggs, Janey L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961220/
https://ncbi.nlm.nih.gov/pubmed/29847655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23536
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