Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering

The phage Mu DNA transposition system provides a versatile species non-specific tool for molecular biology, genetic engineering and genome modification applications. Mu transposition is catalyzed by MuA transposase, with DNA cleavage and integration reactions ultimately attaching the transposon DNA...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Rasila, Tiina S, Pulkkinen, Elsi, Kiljunen, Saija, Haapa-Paananen, Saija, Pajunen, Maria I, Salminen, Anu, Paulin, Lars, Vihinen, Mauno, Rice, Phoebe A, Savilahti, Harri
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961161/
https://ncbi.nlm.nih.gov/pubmed/29294068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1281
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