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H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation
Histone H3 trimethylation at lysine 36 (H3K36me3) is an important histone mark involved in both transcription elongation and DNA mismatch repair (MMR). It is known that H3K36me3 recruits the mismatch-recognition protein MutSα to replicating chromatin via its physical interaction with MutSα's PW...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961058/ https://ncbi.nlm.nih.gov/pubmed/29610279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002839 |
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