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H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation
Histone H3 trimethylation at lysine 36 (H3K36me3) is an important histone mark involved in both transcription elongation and DNA mismatch repair (MMR). It is known that H3K36me3 recruits the mismatch-recognition protein MutSα to replicating chromatin via its physical interaction with MutSα's PW...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961058/ https://ncbi.nlm.nih.gov/pubmed/29610279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002839 |
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