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Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast

Correct localization of the centromeric histone variant CenH3/CENP-A/Cse4 is an important part of faithful chromosome segregation. Mislocalization of CenH3 could affect chromosome segregation, DNA replication and transcription. CENP-A is often overexpressed and mislocalized in cancer genomes, but th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hewawasam, Geetha S, Dhatchinamoorthy, Karthik, Mattingly, Mark, Seidel, Chris, Gerton, Jennifer L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961020/
https://ncbi.nlm.nih.gov/pubmed/29522205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky169
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