The characteristics of 76 atypical neurofibromas as precursors to neurofibromatosis 1 associated malignant peripheral nerve sheath tumors

BACKGROUND: Neurofibromatosis 1 (NF1) leads to the development of benign and malignant peripheral nerve sheath tumors (MPNST). MPNST have been described to develop in preexisting benign plexiform neurofibromas (PN) and have a poor prognosis. Atypical neurofibromas (ANF) were recently described as pr...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Higham, Christine S, Dombi, Eva, Rogiers, Aljosja, Bhaumik, Sucharita, Pans, Steven, Connor, Steve E J, Miettinen, Markku, Sciot, Raf, Tirabosco, Roberto, Brems, Hilde, Baldwin, Andrea, Legius, Eric, Widemann, Brigitte C, Ferner, Rosalie E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961015/
https://ncbi.nlm.nih.gov/pubmed/29409029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy013
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