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The roles of cytochrome P450 and P-glycoprotein in the pharmacokinetics of florfenicol in chickens

The effects of three selective oral inhibitors, fluvoxamine (FLU), ketoconazole (KET), and verapamil (VER), on the pharmacokinetics (PK) of florfenicol (FFC) were investigated in chickens. The chickens were administered orally with saline solution (SAL), FLU (60 mg/kg), KET (25 mg/kg), or VER (9 mg/...

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Vydáno v:Iran J Vet Res
Hlavní autoři: Wang, G. Y., Zheng, H. H., Zhang, K. Y., Yang, F., Kong, T., Zhou, B., Jiang, Sh. X.
Médium: Artigo
Jazyk:Inglês
Vydáno: School of Veterinary Medicine, University of Shiraz 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960766/
https://ncbi.nlm.nih.gov/pubmed/29805456
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