Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca(2+) microscopy

OBJECTIVE: Cardiomyocytes derived from human-induced pluripotent stem cells are a powerful platform for high-throughput drug screening in vitro. However, current modalities for drug testing, such as electrophysiology and fluorescence imaging have inherent drawbacks. To circumvent these problems, we...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Suzuki, Kazushi, Onishi, Takahito, Nakada, Chieko, Takei, Shunsuke, Daniels, Matthew J., Nakano, Masahiro, Matsuda, Tomoki, Nagai, Takeharu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960208/
https://ncbi.nlm.nih.gov/pubmed/29776438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3421-7
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