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Regulation of IgE activity in inhalational tolerance via formation of IgG anti-IgE/IgE immune complexes

BACKGROUND: Allergic asthma is an inflammatory disorder of the airways that results from inappropriate production of IgE against harmless, environmental antigens. Sequestration of free IgE using humanized IgG anti-IgE is an effective therapy for asthma and other atopic disorders. However, the status...

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Publicado en:Clin Mol Allergy
Autores principales: Bracken, Sonali J., Adami, Alexander J., Rafti, Ektor, Schramm, Craig M., Matson, Adam P.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960149/
https://ncbi.nlm.nih.gov/pubmed/29796009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12948-018-0091-x
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